The AGT gene codes for the angiotensinogen protein, a key regulator of blood pressure and body fluid homeostasis. Individuals carrying two copies of the rs699 C allele are at increased risk of hypertension-related disorders such as high blood pressure and stroke. A more recent study shows that variants may also play a significant role in cardiovascular related phenotypes in atherosclerotic peripheral arterial obstructive disease in males. (Source 1)